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The phase i study consists of introducing the vaccine candidate to assess its safety in healthy people.

Vaccine scar on shoulder. Heres an indicative timeline for. Fortunately we already have a head start on the first phase of vaccine development. In phase iii the vaccine is given to thousands of people and tested for efficacy and safety.

Moderna began phase 3 of its trial on july 27 and then enrolled about 15000 participants a month later. Baker an anchor at cnn affiliate wtoc in savannah was the first of 30000 people in the phase 3 study half of whom would get the active vaccine and half a placebo. Previous work to develop a vaccine against the coronavirus diseases sars and mers established knowledge about the structure and function of coronaviruses which accelerated development during early 2020 of varied technology platforms for a covid19.

A vaccine phase i trial involves normal healthy subjects each tested with either the candidate vaccine or a control treatment typically a placebo or an adjuvant containing cocktail or an established vaccine which might be intended to. The timeline on some of the most promising covid 19 vaccine and treatments under development right now published thu may 7 2020 854 am edt updated thu may 7 2020 945 am edt dennis obrien. The trial is designed for people to receive a second shot either three or four weeks later.

In addition astrazeneca launched phase 3 trials in brazil south africa and the united states. Until a vaccine is given to the general population all potential adverse events cannot be anticipated. During phase i small groups of people receive the trial vaccine.

The outbreaks of sars and mers which are also caused by coronaviruses spurred lots of research. Thus many vaccines undergo phase 4 studies formal studies on a vaccine once it is on the. In phase ii the clinical study is expanded and vaccine is given to people who have characteristics such as age and physical health similar to those for whom the new vaccine is intended.

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