Post Exposure Anti Rabies Vaccine Schedule, National Guidelines For Rabies Prophylaxis In India

The health care provider can help determine if the person should receive post exposure rabies vaccination.

Pfizer vaccine eua. The disease is preventable with rapid administration of post exposure prophylaxis pep after exposure however many of those persons affected by rabies are faced with vaccine shortages or cost prohibitive prices for treatment. Prompt rabies pep combining wound care infiltration of rig into and around the wound and multiple doses of rabies cell culture vaccine continue to be highly effective in preventing human rabies. For people who have never been vaccinated against rabies previously postexposure prophylaxis pep should always include administration of both hrig and rabies vaccine.

Postexposure prophylaxis pep consists of a dose of human rabies immune globulin hrig and rabies vaccine given on the day of the rabies exposure and then a dose of vaccine given again on days 3 7 and 14. Previously vaccinated persons are those who have received one of the recommended preexposure or postexposure regimens of hdcv rva or pcecv or those who received another vaccine and had a. Rabies post exposure prophylaxis healthy immunocompetent persons including pregnant women pdf.

Recommendations for pre exposure prophylaxis also remain unchanged with 3 doses of vaccine administered on days 0 7 and 21 or 28. Modern vaccines of cell culture or embryonated egg origin are safer and more effective than the older vaccines which were produced in brain tissue. 5 i u m l titre 05 iuml rabies post exposure prophylaxis pep dose schedule rig rabies immune globulin volume based on.

Intramuscular regimens for rabies post exposure prophylaxis there are 3 intramuscular schedules for category ii and iii exposures. The 5 dose regimen the 2 1 1 regimen the 4 dose regimen with rig in both categories ii and iii vaccines should be injected into the deltoid muscle for adults and children aged 2 years and more. If exposed to rabies previously vaccinated persons should receive two im doses 10 ml each of vaccine one immediately and one three days later.

A person who is exposed and has never been vaccinated against rabies should get 4 doses of rabies vaccine. The person should also get another shot called rabies immune globulin rig. Vaccine day 03714 and 28 rabies immune globulin rig based on body weight day 0 4 doses vaccine day 03714 discontinue immunization after day 3 dose of vaccine day 714 not necessary t i t r e 0.

Rabies immunoglobulin is used only for post exposure prophylaxis. The vaccines used for pre exposure and post exposure vaccination are the same but the immunization schedule differs. Many countries still use intramuscular vaccine pep schedules which require 4 5 vials of vaccine to complete a full.

First rabies vaccine dose to be given immediately after being bitten or getting in contact with the saliva of an infected animal the second dose is given on the third day.