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A brief historical perspective on smallpox disease and preventive efforts since antiquity is followed by an overview of 19 th century efforts to replace variolation.

Covid vaccine approved by who. Presentation live attenuated bcg vaccine bacillus calmette guerin strain each 01 ml contains between. Bcg vaccine offers protection against covid in elderly. Back in india too there has been examples where bcg vaccine proved useful in prevention of covid 19.

Bcg vaccine freeze dried should be stored in dark between 20c and 80c. Of these 25 were sputum positive posing a serious threat of transmitting the infection to children. Icmr study icmr scientists have been investigating the impact of bcg vaccination on the frequencies of immunity cells and total antibody.

The main use of bcg is for vaccination against tuberculosisbcg vaccine can be administered after birth intradermally. It is even more stable if stored in temperatures as low as 200c. Tuberculosis is a major global public health problem with 8 million new cases of pulmonary tuberculosis in the world per year and 289 million deaths.

The history of the bcg vaccine nearly came to an end in 1930 when the lubeck disaster occurred. Bcg vaccination can cause a false positive mantoux test although a very high grade reading is usually due to active disease. Indias low covid 19 case load has been partly attributed to bcg vaccination that is a part of the national immunisation programme for about 50 years.

In india in 1989 the approximate morbidity of tuberculosis was 2 ie there were 15 million cases of pulmonary tuberculosis. This also cast doubts on the safety of bcg. This review documents the history of vaccines and vaccination in india with an objective to derive lessons for policy direction to expand the benefits of vaccination in the country.

The most controversial aspect of bcg is the variable efficacy found in different clinical trials which appears to depend on geography. New delhi oct 30 ians the bacille calmette guerin or bcg vaccine originally made against tuberculosis may help in the management of covid 19 especially in the elderly says a study by the. 1x105 and 33x105 cfu.

In the german city of lubeck 252 infants were given bcg that came originally from the pasteur institute in paris but it was prepared for administration in the tb laboratory in lubeck. India begins study on bcg vaccine impact on covid 19 the study will involve around 1000 healthy volunteers above 60 years of age in six states that have reported a high covid 19 disease burden so.

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