Bcg Vaccine Dose For Newborn, The Place Of Bcg Vaccine In The Management Of Infants Born Of Tuberculous Mothers Nejm

In countries where tuberculosis or leprosy is common one dose is recommended in healthy babies as close to the time of birth as possible.

Pfizer vaccine update india. Bacillus calmetteguerin bcg vaccine is a vaccine primarily used against tuberculosis tb. The standard dose of bcg vaccine is 01mg in 1 ml though manufacturers of certain strains of bcg ie copenhagen 1331 recommend half dose in infants. Bcg vaccine vial of 20 doses 005 ml for infants under one year old to be reconstituted with 1 ml of sodium chloride injection.

Birth or anytime after birth. Bcg vaccine vial of 10 doses 005 ml for infants under one year old to be reconstituted with 05 ml of sodium chloride injection. Children 1 month and older.

For example when bcg vaccine is given to a newborn baby the amount of dose could be as low as 005ml for intradermal injection. Neonates 1 month. Intradermal injection of bcg vaccine reduces the risk of neurovascular injury.

Healthcare professionals shall refer to the product insert for the recommended dose for the individual age group. Therefore to reduce vaccine wastage a 20 dose vial of bcg is often only opened if at least 1012 infants are present jeopardising bcg vaccination coverage and timely vaccination. In infants less than 1 month old the dosage of bcg vaccine should be reduced by one half by using 2 ml of sterile water for injection usp at 4 250c 39 770f when reconstituting.

Drop 02 to 03 ml of vaccine from syringe onto cleansed deltoid and spread over a 1 to 2 inch area using the edge of the multiple puncture device prepare vaccine clean skin administration site on deltoid with alcohol or acetone sponge and allow to dry thoroughly. Right deltoid region of the arm bcg given at earliest possible age protects the possibility of tb meningitis and other tb infections in which infants are prone. A short narrow needle 15 mm 26 gauge is needed for bcg vaccine.

The reconstituted vaccine is discarded after 46 hours. Carefully invert the vial a few times to resuspend freeze dried bcg. There are also varying ideas about the optimum time to vaccinate babies and some studies suggest that late vaccination confers a high degree of protection.

Usual pediatric dose for tuberculosis prophylaxis. In areas where tuberculosis is not common only children at high risk are typically immunized while suspected cases of tuberculosis are individually tested for. Health workers say that bcg is the most difficult vaccine to administer due to the small size of newborns arms.

If a vaccinated infant remains tuberculin negative to 5 tu on skin testing and if indications for vaccination persist the infant should receive a full dose after 1 year of age. Then 02 to 03 ml of the diluted solution is dropped on the skin and administered using a multiple puncture disc. Bcg is the only vaccine with this route of administration.