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Influenza vaccine available in pakistan. Bcg vaccine bese je a preparation used to immunize individuals against tuberculosis consisting of attenuated live human tubercle bacilli mycobacterium tuberculosis the bacteria that cause tuberculosis. Bcg is used in many countries with a high prevalence of tb to prevent childhood tuberculous meningitis and miliary disease. Bcg vaccination can cause a false positive mantoux test although a very high grade reading is usually due to active disease.
Bcg vaccine has a documented protective effect against meningitis and disseminated tb in children. It is equally effective in giving protection against leprosy. Tuberculosis which causes the diseasethe vaccine was developed over a period of 13 years from 1908 to 1921 by french bacteriologists albert calmette and camille guerin who named the product bacillus calmette guerin or bcg.
Bcg vaccine for percutaneous use is an attenuated live culture preparation of the bacillus of calmette and guerin bcg strain of mycobacterium bovis. Bacille calmette guerin bcg vaccination has been used to prevent tuberculosis since 1921 and it was incorporated in the world health organisations expanded programme on immunisation in 1974 to strengthen the fight against childhood tuberculosis in developing countries. The most controversial aspect of bcg is the variable efficacy found in different clinical trials which appears to depend on geography.
The vaccine is used to confer a measure of immunity on people who on mantoux or heaf testing are shown not to have had a primary infection with tuberculosis. Bcg vaccine is recommended if you live with or have close contact with someone who is infected with tuberculosis. Bcg vaccine vaccine against tuberculosisthe bcg vaccine is prepared from a weakened strain of mycobacterium bovis a bacteria closely related to m.
Many foreign born persons have been bcg vaccinated. The main use of bcg is for vaccination against tuberculosisbcg vaccine can be administered after birth intradermally. Bcg vaccine is used to help prevent tuberculosis tb in adults and children who have never had this disease and test negative for tuberculosis.
1 though there are controversies regarding its efficacy it is generally agreed that the vaccine is effective against the disseminated disease and meningitis in childhood tuberculosis. 1 the tice strain used in this bcg vaccine preparation was developed at the university of illinois from a strain originated at the pasteur institute. Bcg or bacille calmette guerin is a vaccine for tuberculosis tb disease.
Although the mechanism of its anti tumor activity is unclear immunization with bcg vaccine likely activates a th1 cytokine response that includes the induction of interferon.
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